A woman with a BMI of 34 kg/m² uses a combined oral contraceptive and is starting tirzepatide, with dose increases planned at four-week intervals.

Question

A woman with a BMI of 34 kg/m² uses a combined oral contraceptive and is starting tirzepatide, with dose increases planned at four-week intervals. She has no vomiting or diarrhoea. Which additional contraceptive schedule matches current MHRA advice?

Accepted Answer

Use condoms for four weeks after starting and four weeks after every dose increase

Answer

Use condoms for four weeks after starting, then use the oral contraceptive alone during dose increases

Answer

Use condoms for four weeks after any vomiting or diarrhoea during dose escalation

Answer

Use condoms throughout treatment and for three months after the final tirzepatide dose

Answer

Use condoms for seven days after starting and seven days after every dose increase

Macrogol in frail renal patient — GPhC CRA MCQ

A woman with a BMI of 34 kg/m² uses a combined oral contraceptive and is starting tirzepatide, with dose increases planned at four-week intervals. She has no vomiting or diarrhoea. Which additional contraceptive schedule matches current MHRA advice?