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Thyroid over-replacement — GPhC CRA MCQ

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ModerateEndocrine TherapeuticsThyroid over-replacementGPhC CRA

A 59-year-old patient taking levothyroxine reports palpitations, weight loss and tremor. Their repeat prescription increased accidentally from 100 micrograms to 200 micrograms daily for 6 weeks. They feel anxious but stable. What is the most appropriate action?

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Correct answer: E — Contact the prescriber promptly for dose review and thyroid tests

Symptoms and the dosing history suggest possible levothyroxine over-replacement. The prescriber should review dose and arrange thyroid function testing. Unauthorised beta-blocker supply or prolonged continuation could lead to avoidable harm.

Reference: BNF; NICE CKS