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Brand continuity antiepileptic — GPhC CRA MCQ

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HardDispensing and SupplyBrand continuity antiepilepticGPhC CRA

A patient stabilised on modified-release carbamazepine receives a prescription written generically. The pharmacy has changed supplier and a different brand is available today. What is the legal classification/requirement?

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Correct answer: B — Consider maintaining the same brand and discuss any change with the patient

For some antiepileptic medicines, continuity of a specific manufacturer's product may be clinically important. Carbamazepine is commonly treated as a medicine where brand consistency should be considered. The pharmacist should assess supply, counsel the patient and liaise with the prescriber where needed. Switching to immediate-release tablets would not be an equivalent substitution.

Reference: BNF; MHRA Drug Safety Update