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Enoxaparin renal impairment — GPhC CRA MCQ

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ModerateRenal and Hepatic ImpairmentEnoxaparin renal impairmentGPhC CRA

A patient discharged after surgery presents a prescription for enoxaparin prophylaxis. The discharge summary records eGFR 24 mL/min/1.73 m², but the dose appears to be the usual prophylactic adult dose. What is the most appropriate action?

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Correct answer: B — Query the dose because renal impairment may require adjustment

Low molecular weight heparins are renally cleared and can accumulate in significant renal impairment, increasing bleeding risk. Dose adjustment or an alternative strategy may be required depending on local guidance and indication. Bruising should prompt review rather than dose escalation. Enoxaparin is administered by injection, not orally.

Reference: https://www.pharmacyregulation.org/students-and-trainees/pharmacist-education-and-training/registration-assessment