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Anti-diarrhoeal and ulcerative colitis — GPhC CRA MCQ

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HardGastrointestinal TherapeuticsAnti-diarrhoeal and ulcerative colitisGPhC CRA

A patient with known ulcerative colitis asks to buy loperamide during a flare with six bloody stools daily and abdominal pain. They are awaiting a call from their IBD nurse. What is the most appropriate action?

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Correct answer: A — Do not supply and advise urgent IBD clinical review

Bloody diarrhoea and abdominal pain in ulcerative colitis may represent an active flare requiring clinical assessment. Antimotility medicines can be unsafe in significant colitis because of toxic megacolon risk. Stopping mesalazine without review may worsen disease control. NSAIDs can exacerbate IBD and increase gastrointestinal harm.

Reference: NICE CKS; BNF