Antifungal in pregnancy — GPhC CRA MCQ
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Correct answer: A — Do not supply oral fluconazole; arrange supervised topical treatment and advise insertion without an applicator
The fluconazole SmPC says standard short-course treatment should not be used in pregnancy unless clearly necessary. A vaginal clotrimazole product can be used in pregnancy only under physician or midwife supervision, and the tablet should be inserted without an applicator. Therefore the pharmacist should not make a casual OTC systemic supply and should arrange appropriate supervised topical treatment and safety-netting.
Reference: Fluconazole Summary of Product Characteristics: https://www.medicines.org.uk/emc/product/4438/smpc; Clotrimazole vaginal tablet Summary of Product Characteristics: https://www.medicines.org.uk/emc/product/11464/smpc