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Antifungal in pregnancy — GPhC CRA MCQ

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HardInfectionsAntifungal in pregnancyGPhC CRA

A patient at 10 weeks’ gestation has symptoms consistent with vulvovaginal candidiasis and asks for an oral fluconazole capsule. There are no red flags. What is the best pharmacy response?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: ADo not supply oral fluconazole; arrange supervised topical treatment and advise insertion without an applicator

The fluconazole SmPC says standard short-course treatment should not be used in pregnancy unless clearly necessary. A vaginal clotrimazole product can be used in pregnancy only under physician or midwife supervision, and the tablet should be inserted without an applicator. Therefore the pharmacist should not make a casual OTC systemic supply and should arrange appropriate supervised topical treatment and safety-netting.

Reference: Fluconazole Summary of Product Characteristics: https://www.medicines.org.uk/emc/product/4438/smpc; Clotrimazole vaginal tablet Summary of Product Characteristics: https://www.medicines.org.uk/emc/product/11464/smpc