skip to main content

Domperidone QT risk — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

HardGastrointestinal TherapeuticsDomperidone QT riskGPhC CRA

A patient with nausea requests domperidone. Their medication history includes amiodarone and citalopram, and they have a history of prolonged QT interval. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: C — Do not supply and refer for prescriber assessment

Domperidone can prolong the QT interval and is unsuitable in patients with existing QT prolongation or interacting QT-prolonging medicines. Amiodarone and citalopram make the scenario higher risk. The patient should be referred for assessment and an alternative antiemetic plan. Long-term use increases risk and is not appropriate without review.

Reference: BNF; MHRA Drug Safety Update