skip to main content

Adrenal replacement sick-day rules — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

HardEndocrine TherapeuticsAdrenal replacement sick-day rulesGPhC CRA

A patient taking hydrocortisone replacement for adrenal insufficiency asks what to do during a febrile vomiting illness. They have an emergency injection kit at home. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — Follow sick-day rules and seek urgent help if vomiting prevents oral dosing

Patients with adrenal insufficiency need increased steroid cover during significant illness and urgent action if vomiting prevents oral absorption. They should follow their agreed sick-day rules and use emergency injection arrangements where indicated. Stopping or reducing hydrocortisone can precipitate adrenal crisis. Delayed review is unsafe when oral dosing cannot be retained.

Reference: BNF; Society for Endocrinology guidance