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Hypertension thiazide-like diuretic adverse effect — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsHypertension thiazide-like diuretic adverse effectGPhC CRA

A 71-year-old patient taking indapamide for hypertension reports muscle cramps and fatigue. Recent blood tests show sodium 128 mmol/L and potassium 3.2 mmol/L. They also take amlodipine. What is the most appropriate alternative?

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Correct answer: C — Withhold concern and refer to the prescriber for electrolyte disturbance review

Thiazide-like diuretics can cause hyponatraemia and hypokalaemia, which may present with fatigue and cramps. The abnormal electrolytes require clinical review and likely adjustment of therapy. Increasing the diuretic would worsen the problem. Reassurance without action would be unsafe.

Reference: BNF