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GLP-1 receptor agonist counselling — GPhC CRA MCQ

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ModerateEndocrine TherapeuticsGLP-1 receptor agonist counsellingGPhC CRA

A patient starts semaglutide injection for type 2 diabetes and obesity. They ask about common early adverse effects and when to seek help. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: A — Nausea can occur; seek urgent advice for severe persistent abdominal pain

GLP-1 receptor agonists commonly cause gastrointestinal adverse effects, particularly during dose escalation. Severe persistent abdominal pain may indicate pancreatitis and requires urgent medical advice. The dosing schedule is product-specific and must be followed carefully. Extra gliclazide could increase hypoglycaemia risk and would not treat nausea.

Reference: BNF