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Amlodipine oedema — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsAmlodipine oedemaGPhC CRA

A 67-year-old patient started amlodipine 10 mg daily for hypertension. They return with bilateral ankle swelling that is worse by evening, with no breathlessness and stable weight. Their BP is 124/72 mmHg. What is the most appropriate action?

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Correct answer: D — Discuss dose reduction or changing antihypertensive therapy with the prescriber

Peripheral oedema is a common dose-related adverse effect of dihydropyridine calcium-channel blockers. The appropriate response is to assess severity and discuss dose reduction or an alternative antihypertensive with the prescriber. Adding a loop diuretic is often ineffective for this mechanism and should not be supplied without authority. Stopping medicines abruptly may compromise BP control.

Reference: BNF; NICE CKS