skip to main content

Pain neuropathic first-line option — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

ModerateCNS TherapeuticsPain neuropathic first-line optionGPhC CRA

A patient with diabetic neuropathic pain asks whether regular ibuprofen is the best long-term option. They have CKD stage 3 and take ramipril. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: C — Discuss a neuropathic pain option such as duloxetine or amitriptyline with the prescriber

Neuropathic pain often requires specific medicines such as duloxetine, amitriptyline, gabapentin or pregabalin, selected to patient factors and comorbidities. Regular NSAIDs are unsuitable here because of CKD and ACE inhibitor use. Antibiotics and topical steroids do not treat neuropathic pain. The pharmacist should support prescriber review rather than self-treatment with high-risk analgesics.

Reference: NICE CKS; BNF