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PPI review — GPhC CRA MCQ

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ModerateGastrointestinal TherapeuticsPPI reviewGPhC CRA

A patient has taken lansoprazole 30 mg daily for eight months after an episode of reflux. They have no current symptoms and no history of severe oesophagitis. They ask for another repeat supply. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Suggest prescriber review for step-down or stopping if clinically suitable

Long-term PPI therapy should be reviewed to confirm ongoing indication and use the lowest effective dose. Step-down, intermittent treatment or stopping may be suitable in some patients. Sudden stopping can cause rebound symptoms, so counselling and a plan are helpful. NSAIDs may worsen gastrointestinal risk.

Reference: BNF; NICE CKS