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Isotretinoin pregnancy prevention — GPhC CRA MCQ

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HardAdverse Drug Reactions and Drug SafetyIsotretinoin pregnancy preventionGPhC CRA

A patient taking isotretinoin says they missed a pregnancy test appointment but still wants the next supply today. They are within a pregnancy prevention programme. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Do not supply until pregnancy prevention programme requirements are confirmed

Isotretinoin is highly teratogenic and supply is controlled by pregnancy prevention programme requirements. The pharmacist must ensure the required checks and documentation are in place before supply. Large supplies or bypassing testing would increase risk. Contraception advice is a central part of safe use.

Reference: MHRA Isotretinoin guidance; BNF