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Antipsychotic metabolic monitoring — GPhC CRA MCQ

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ModerateCNS TherapeuticsAntipsychotic metabolic monitoringGPhC CRA

A patient started olanzapine 10 mg daily three months ago. They have gained 6 kg and ask whether any checks are needed. Their next mental health appointment is in six weeks. What monitoring is required?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: C — Check weight, glucose or HbA1c, lipids and BP as part of metabolic monitoring

Olanzapine can cause weight gain and metabolic adverse effects, including dyslipidaemia and hyperglycaemia. Monitoring should include weight, BP, glucose or HbA1c and lipids according to local protocols. Early recognition allows treatment review and risk reduction. INR and lithium levels are not relevant unless the patient also takes those medicines.

Reference: BNF; NICE CKS