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NSAID gastroprotection — GPhC CRA MCQ

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ModerateGastrointestinal TherapeuticsNSAID gastroprotectionGPhC CRA

A 74-year-old patient taking naproxen for osteoarthritis also takes aspirin 75 mg daily after a TIA. They have a history of dyspepsia. The GP asks whether gastroprotection is needed. What is the most appropriate alternative?

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Correct answer: DRecommend a proton pump inhibitor for gastroprotection

Older age, concurrent aspirin and NSAID use, and dyspepsia history increase gastrointestinal bleeding risk. A PPI is commonly used for gastroprotection where NSAID therapy is necessary. Adding another NSAID would increase harm. Stopping aspirin after TIA without review may increase vascular risk.

Reference: https://www.pharmacyregulation.org/registration-assessment#stage-8-order-32