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ACE inhibitor angioedema — GPhC CRA MCQ

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ModerateAdverse Drug Reactions and Drug SafetyACE inhibitor angioedemaGPhC CRA

A patient who started perindopril last week presents with swollen lips but no rash. They are speaking in full sentences but feel the swelling is increasing. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Arrange urgent assessment for suspected ACE inhibitor angioedema

ACE inhibitors can cause angioedema, which may occur without urticaria and can threaten the airway. Increasing lip swelling requires urgent assessment. The ACE inhibitor should not be continued without medical review. Antihistamines alone may be insufficient and can delay care.

Reference: BNF; NICE CKS