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Constipation opioid-related — GPhC CRA MCQ

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EasyGastro-intestinal TherapeuticsConstipation opioid-relatedGPhC CRA

A 73-year-old woman taking morphine modified-release has not opened her bowels for four days despite docusate. She has no vomiting or severe abdominal pain. What is the most appropriate alternative?

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Correct answer: D — Add or optimise a stimulant laxative such as senna

Opioid-induced constipation commonly needs regular laxatives, often including a stimulant laxative. Docusate alone may be insufficient. Red flags such as vomiting, severe pain or suspected obstruction would require urgent assessment. Loperamide would worsen constipation.

Reference: BNF; NICE CKS