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GLP-1 receptor agonist adverse effects — GPhC CRA MCQ

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ModerateEndocrine TherapeuticsGLP-1 receptor agonist adverse effectsGPhC CRA

A 49-year-old woman starts semaglutide injection for type 2 diabetes. She reports nausea after the first dose and asks whether this is dangerous. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: E — Eat smaller meals and seek help for severe persistent abdominal pain

Gastrointestinal adverse effects such as nausea are common when starting GLP-1 receptor agonists. Eating smaller meals and avoiding large fatty meals may help. Severe persistent abdominal pain needs urgent assessment because pancreatitis is a rare but important concern. Dose changes and stopping other diabetes medicines should follow prescriber advice.

Reference: BNF; NICE CKS