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Mesalazine monitoring — GPhC CRA MCQ

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ModerateGastro-intestinal TherapeuticsMesalazine monitoringGPhC CRA

A 41-year-old woman starts oral mesalazine for ulcerative colitis. The GP asks what monitoring should be arranged after initiation. What monitoring is required?

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Correct answer: A — Renal function monitoring

Mesalazine can rarely cause renal impairment, including interstitial nephritis. Renal function should be checked before and during treatment according to local guidance and product information. Patients should report unexplained bruising, sore throat or worsening symptoms. The other tests are not routine mesalazine monitoring.

Reference: BNF; NICE CKS