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NSAID renal risk — GPhC CRA MCQ

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EasyMusculoskeletal TherapeuticsNSAID renal riskGPhC CRA

A 76-year-old man with CKD stage 3, heart failure and ramipril asks to buy ibuprofen tablets for knee pain. He is also taking furosemide. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: AAvoid oral ibuprofen and discuss safer analgesic options

NSAIDs can worsen renal function and fluid retention, particularly in older people with CKD and heart failure. The combination with ACE inhibitors and diuretics increases acute kidney injury risk. Safer analgesic options and non-pharmacological measures should be considered. Prescriber review is appropriate if pain control is inadequate.

Reference: BNF; NICE CKS