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Antibiotics and combined hormonal contraception — GPhC CRA MCQ

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ModerateInfectionsAntibiotics and combined hormonal contraceptionGPhC CRA

A 23-year-old woman taking a combined oral contraceptive is prescribed phenoxymethylpenicillin for tonsillitis. She asks if she needs extra contraception. What would you advise the patient?

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Correct answer: EExtra contraception is not routinely needed unless vomiting or diarrhoea affects pill absorption

Most non-enzyme-inducing antibiotics do not reduce combined oral contraceptive efficacy. Vomiting or severe diarrhoea can affect absorption, so missed-pill guidance may apply. Enzyme-inducing medicines are different and require specific contraceptive advice. Phenoxymethylpenicillin is not an enzyme inducer.

Reference: FSRH; BNF