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Clonidine withdrawal risk — GPhC CRA MCQ

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HardCardiovascular TherapeuticsClonidine withdrawal riskGPhC CRA

A 64-year-old woman taking clonidine 100 micrograms twice daily for refractory hypertension requests an emergency supply after leaving her tablets on holiday. The GP record confirms stable long-term use. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: D — Consider an emergency supply because abrupt withdrawal can cause rebound hypertension

Abrupt withdrawal of clonidine can cause rebound hypertension and sympathetic symptoms. Where legal and professional requirements are met, an emergency supply may prevent avoidable harm. The pharmacist should check dose, duration, identity and immediate need, and make the required record. Pseudoephedrine may raise blood pressure and is not a substitute.

Reference: BNF