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NSAID hypersensitivity in asthma — GPhC CRA MCQ

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ModerateAdverse Drug Reactions and Drug SafetyNSAID hypersensitivity in asthmaGPhC CRA

A 33-year-old woman with asthma and nasal polyps asks for aspirin for a viral headache. She says ibuprofen previously made her wheezy. What is the most appropriate action?

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Correct answer: C — Avoid aspirin and recommend a safer analgesic if suitable

NSAID-exacerbated respiratory disease can occur in people with asthma and nasal polyps. A previous wheeze with ibuprofen suggests risk with aspirin and other NSAIDs. Paracetamol may be safer if suitable and tolerated. Desensitisation requires specialist supervision.

Reference: BNF; NICE CKS