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DMARD infection advice — GPhC CRA MCQ

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ModerateMusculoskeletal TherapeuticsDMARD infection adviceGPhC CRA

A 62-year-old woman taking methotrexate and adalimumab for rheumatoid arthritis has a fever and productive cough. She asks whether to use leftover antibiotics at home. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: A — Seek medical advice promptly because immunosuppression increases infection risk

Methotrexate and biologic therapy can increase susceptibility to infection and may affect how infections present. Fever and productive cough warrant prompt medical assessment. Leftover antibiotics are inappropriate and may delay proper care. Live vaccines may be contraindicated with significant immunosuppression.

Reference: BNF; NICE CKS