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Antipsychotic metabolic monitoring — GPhC CRA MCQ

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ModerateCNS TherapeuticsAntipsychotic metabolic monitoringGPhC CRA

A 36-year-old man has started olanzapine 10mg at night. He collects his second prescription and mentions increased appetite and weight gain. What monitoring is required?

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Correct answer: EWeight, glucose or HbA1c, lipids and blood pressure

Olanzapine can cause weight gain and metabolic adverse effects. Baseline and ongoing monitoring should include weight, glycaemic status, lipids and blood pressure. Early lifestyle advice and prescriber review are important if weight gain emerges. The other monitoring sets do not match the main risks of olanzapine.

Reference: BNF; NICE CKS