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Gabapentin renal dose — GPhC CRA MCQ

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ModerateRenal and Hepatic ImpairmentGabapentin renal doseGPhC CRA

A 74-year-old woman with eGFR 29 mL/min/1.73m2 is prescribed gabapentin 300mg three times daily for neuropathic pain. She reports dizziness after the first day. What monitoring is required?

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Correct answer: A — Renal function and signs of CNS toxicity such as dizziness or sedation

Gabapentin is renally eliminated and dose adjustment is required in renal impairment. Dizziness and sedation can indicate poor tolerability and increase fall risk in older people. Renal function and CNS adverse effects are the key monitoring priorities. The other tests do not guide gabapentin dosing or toxicity assessment.

Reference: BNF