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Enoxaparin renal dosing — GPhC CRA MCQ

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ModerateRenal and Hepatic ImpairmentEnoxaparin renal dosingGPhC CRA

A 79-year-old man with eGFR 24 mL/min/1.73m2 is prescribed enoxaparin for treatment-dose anticoagulation after pulmonary embolism. The ward asks pharmacy what to check. What monitoring is required?

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Correct answer: D — Renal function and bleeding risk, with dose suitability review

Low molecular weight heparins are renally cleared to varying degrees, and accumulation can increase bleeding risk in renal impairment. Dose adjustment or alternative anticoagulation may be needed depending on indication and renal function. Anti-Xa monitoring may be considered in selected specialist settings. Routine respiratory or vitamin monitoring does not address the risk.

Reference: BNF