skip to main content

Levothyroxine administration — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

EasyEndocrine TherapeuticsLevothyroxine administrationGPhC CRA

A 43-year-old woman starts levothyroxine 50 micrograms daily for hypothyroidism. She also takes calcium carbonate tablets with breakfast. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — Take levothyroxine on an empty stomach and separate it from calcium

Levothyroxine absorption can be reduced by calcium and iron salts. It is usually taken consistently on an empty stomach, commonly before breakfast, with separation from interacting medicines. Consistency of administration is important for stable thyroid function tests. As-needed use is inappropriate.

Reference: BNF; NICE CKS