skip to main content

Hepatic impairment and paracetamol risk — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

ModerateRenal and Hepatic ImpairmentHepatic impairment and paracetamol riskGPhC CRA

A 58-year-old man with alcohol-related liver cirrhosis asks to buy the largest pack of paracetamol for chronic abdominal pain. He also takes co-codamol prescribed by his GP. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: D — Refer for assessment and check total paracetamol exposure

Cirrhosis and alcohol history increase concern about analgesic safety and underlying pain cause. Co-codamol already contains paracetamol, so duplicate paracetamol exposure must be avoided. NSAIDs can be hazardous in cirrhosis due to bleeding, renal and fluid risks. The patient needs clinical review and clear total daily dose advice.

Reference: BNF