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Amiodarone safety monitoring — GPhC CRA MCQ

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HardCardiovascular TherapeuticsAmiodarone safety monitoringGPhC CRA

A patient taking essential amiodarone has tiredness and weight gain. Tests show raised TSH and low free T4 without severe symptoms. Which interpretation is most appropriate?

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Correct answer: BAmiodarone-induced hypothyroidism; review thyroid replacement and cardiac therapy

Raised TSH with low free T4 indicates hypothyroidism. Amiodarone does not always need to be stopped when it is essential; thyroid replacement and continued cardiac treatment may be appropriate after prescriber or specialist review. Abrupt unsupervised withdrawal is not indicated.

Reference: BNF: amiodarone hydrochloride: https://bnf.nice.org.uk/drugs/amiodarone-hydrochloride/