Spironolactone hyperkalaemia — GPhC CRA MCQ
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Correct answer: E — Potassium citrate may worsen hyperkalaemia with spironolactone and ramipril
Spironolactone and ACE inhibitors can increase serum potassium. Adding a potassium-containing preparation may further increase the risk of hyperkalaemia. The patient's recent potassium is already high-normal, which strengthens the need to avoid casual supply and refer. The other options do not describe the main clinically relevant risk.
Reference: BNF; NICE CKS