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Labelling methotrexate — GPhC CRA MCQ

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ModerateDispensing and SupplyLabelling methotrexateGPhC CRA

A patient prescribed methotrexate 2.5mg tablets takes six tablets once weekly on Friday. The dispensing label generated by the system reads 'take as directed'. What is the legal classification/requirement?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: D — Amend the label to state the weekly dose clearly and counsel the patient

Methotrexate dosing errors can be fatal, and labels should clearly state the weekly dose and day where appropriate. 'Take as directed' is unsafe for methotrexate unless there is no alternative and robust counselling is documented. Patient understanding should be confirmed at each supply. Folic acid use and monitoring should also be checked.

Reference: BNF; MEP