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DOAC renal monitoring — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsDOAC renal monitoringGPhC CRA

A 78-year-old woman takes rivaroxaban 20mg once daily for atrial fibrillation. Her eGFR has fallen from 62 to 34 mL/min/1.73m2 over eight months. A repeat prescription is due today. What monitoring is required?

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Correct answer: BRenal function should be reviewed to confirm the dose remains appropriate

Renal function affects rivaroxaban exposure and dose suitability. A fall in eGFR may require dose review or reconsideration of anticoagulant choice depending on indication and local guidance. INR monitoring does not measure rivaroxaban anticoagulant effect for routine care. The pharmacist should prompt prescriber review rather than ignore the renal change.

Reference: BNF; NICE CKS