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Opioid constipation prophylaxis — GPhC CRA MCQ

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EasyCNS TherapeuticsOpioid constipation prophylaxisGPhC CRA

A 70-year-old woman starts modified-release morphine for cancer pain. She asks why the prescription also includes senna tablets. What is the most appropriate alternative?

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Correct answer: C — Explain that regular laxative treatment helps prevent opioid-induced constipation

Constipation is a predictable adverse effect of opioids and tolerance usually does not develop to this effect. A stimulant laxative is commonly co-prescribed, sometimes with an osmotic laxative depending on symptoms. The patient should also receive counselling on drowsiness, driving and safe storage. Senna does not prevent dependence or reverse sedation.

Reference: BNF; NICE CKS