Nitrofurantoin renal function — GPhC CRA MCQ
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Correct answer: A — Contact the prescriber because renal function and upper UTI symptoms need review
Nitrofurantoin is not suitable for suspected upper urinary tract infection because tissue penetration is inadequate. Renal function also affects suitability, with caution or avoidance depending on eGFR and treatment context. Fever and flank pain suggest pyelonephritis and need medical assessment. The pharmacist should contact the prescriber urgently.
Reference: BNF; NICE CKS