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Gabapentin misuse and respiratory risk — GPhC CRA MCQ

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ModerateCNS TherapeuticsGabapentin misuse and respiratory riskGPhC CRA

A 69-year-old man with COPD takes morphine modified-release and presents a new prescription for gabapentin for neuropathic pain. He seems drowsy and says he fell yesterday. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: E — Contact the prescriber to discuss CNS and respiratory depression risk

Gabapentin can cause sedation and dizziness, and the risks are increased with opioids and respiratory disease. A recent fall and drowsiness are warning signs that require prescriber review. Pregabalin would have similar CNS depressant concerns. Extra opioid or alcohol would increase harm.

Reference: BNF; MEP