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Lithium routine monitoring — GPhC CRA MCQ

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ModerateCNS TherapeuticsLithium routine monitoringGPhC CRA

A 52-year-old woman on long-term lithium asks why she needs regular blood tests when her mood has been stable for years. What monitoring is required?

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Correct answer: B — Lithium level, renal function and thyroid function

Lithium has a narrow therapeutic index, so serum levels must be monitored to maintain efficacy and reduce toxicity. Renal function is important because lithium is renally cleared and may impair renal function over time. Thyroid dysfunction can also occur during long-term treatment. Stable mood does not remove the need for monitoring.

Reference: BNF; NICE CKS