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Familial hypercholesterolaemia referral — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsFamilial hypercholesterolaemia referralGPhC CRA

A 32-year-old man asks about a private cholesterol result showing total cholesterol 8.9 mmol/L and LDL cholesterol 6.2 mmol/L. His father had a myocardial infarction aged 42. He takes no regular medicines. What is the most appropriate action?

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Correct answer: A — Advise GP assessment for possible familial hypercholesterolaemia

Very high LDL cholesterol with premature coronary disease in a first-degree relative suggests possible familial hypercholesterolaemia. The patient needs formal assessment and likely specialist or GP-led management. Lifestyle advice is useful but would not be sufficient as the sole action. Statins are not supplied over the counter at high dose for this purpose.

Reference: NICE CKS