skip to main content

Amoebic dysentery — DTM&H MCQ

Instant feedback + full explanation. One question, done properly.

HardProtozoal InfectionsAmoebic dysenteryDTM&H

Stool PCR confirms Entamoeba histolytica in a traveller with dysentery, and trophozoites containing erythrocytes are seen. Which pharmacological sequence best prevents persistence after treating tissue invasion?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: D — A tissue-active nitroimidazole followed by a luminal amoebicide

The best answer is “A tissue-active nitroimidazole followed by a luminal amoebicide”. A nitroimidazole treats invasive trophozoites in the bowel wall and extra-intestinal sites, but a subsequent luminal agent is required to eradicate intraluminal organisms and reduce relapse or transmission. A luminal agent alone is inadequate for dysentery with tissue invasion.

Reference: WHO Model Formulary: invasive amoebiasis: https://iris.who.int/bitstream/10665/44053/1/9789241547659_eng.pdf