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Toxic shock syndrome — ABEM Board MCQ

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ModerateInfectious disease emergenciesToxic shock syndromeABEM Board

A 25-year-old woman arrives with fever, vomiting, diarrhea, and diffuse rash. Triage acuity is ESI 1; T 103.8 F, BP 78/40 mm Hg, HR 144/min. She is menstruating and uses tampons. Exam shows diffuse erythroderma and mucous membrane hyperemia. Which of the following is the most appropriate next step in management?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: D — Start IV fluids, broad anti-staphylococcal antibiotics with toxin suppression, and source control

Toxic shock syndrome requires resuscitation, antibiotics including toxin-suppressing therapy such as clindamycin, and removal or drainage of the source.

Reference: CDC toxic shock syndrome guidance; IDSA SSTI guideline