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Opioid overdose — ABEM Board MCQ

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EasyToxicologyOpioid overdoseABEM Board

A 36-year-old man is found unresponsive in a restroom. Triage acuity is ESI 1; RR 6/min, SpO2 78%, HR 54/min, BP 104/62 mm Hg. Pupils are pinpoint and there are needle tracks. Bag-mask ventilation has been started. Which of the following is the most important immediate intervention?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: DAdminister naloxone titrated to adequate ventilation

Opioid toxicity causes respiratory depression and miosis; naloxone should be titrated to restore ventilation while supporting the airway.

Reference: ACEP Opioids clinical policy; CDC opioid overdose guidance