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Wernicke encephalopathy — ABEM Board MCQ

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ModerateNeurological emergenciesWernicke encephalopathyABEM Board

A 49-year-old man with alcohol use disorder arrives confused and ataxic. Triage acuity is ESI 2; BP 132/78 mm Hg, HR 112/min, glucose 66 mg/dL. He has horizontal nystagmus and poor nutrition. IV dextrose is being prepared. Which of the following is the most important immediate intervention?

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Correct answer: AGive IV thiamine before or with dextrose

Confusion, ataxia, and ophthalmoplegia in a malnourished patient suggest Wernicke encephalopathy; thiamine should accompany glucose.

Reference: ACEP toxicology and neurologic emergency references