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Systemic juvenile idiopathic arthritis — SCE Rheumatology MCQ

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HardPaediatric rheumatologySystemic juvenile idiopathic arthritisSCE Rheumatology

A patient with Behçet syndrome develops headache and papilloedema. MR venography confirms cerebral venous-sinus thrombosis, and arterial imaging shows no aneurysm. What is the principal acute disease-directed treatment?

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Correct answer: A — High-dose glucocorticoid with specialist immunosuppressive treatment

Cerebral venous thrombosis in Behçet syndrome reflects inflammatory vascular disease. High-dose glucocorticoid with appropriate immunosuppression is central; anticoagulation is individualised after excluding pulmonary or other arterial aneurysm and assessing bleeding risk.

Reference: BAD/BSR living guideline for managing Behçet syndrome (Published January 2025): https://academic.oup.com/rheumatology/article/64/1/74/7733834; EULAR recommendations for management of Behçet syndrome (Published 2018): https://ard.bmj.com/content/77/6/808