Sarcoid arthropathy — SCE Rheumatology MCQ

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HardPregnancy in Rheumatic Disease, Rare ConditionsSarcoid arthropathySCE Rheumatology

A patient has acute bilateral ankle arthritis, erythema nodosum, fever and bilateral hilar lymphadenopathy. Which diagnosis best unifies the presentation?

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Correct answer: B — Löfgren syndrome

The triad of bilateral hilar lymphadenopathy, erythema nodosum and acute ankle periarthritis is Löfgren syndrome, an acute sarcoid phenotype. Alternative infection and lymphoma are considered when the course or imaging is atypical.

Reference: BTS clinical statement on pulmonary sarcoidosis (Published 2020): https://www.brit-thoracic.org.uk/clinical-resources/clinical-statements/sarcoidosis/; ATS clinical practice guideline for diagnosis and detection of sarcoidosis (Published 2020): https://academic.oup.com/ajrccm/article/201/8/e26/8496541