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Kawasaki disease — SCE Rheumatology MCQ

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EasyPaediatric RheumatologyKawasaki diseaseSCE Rheumatology

A 3-year-old boy has fever for 7 days, conjunctivitis, cracked lips, rash and swollen hands. CRP is 140 mg/L and platelets are rising. Echocardiography is arranged. There is no alternative source of infection. What is the most appropriate management?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: EGive intravenous immunoglobulin and aspirin under specialist care

Explanation lettering: E = shown as A · D = shown as B · B = shown as D · A = shown as E

Give intravenous immunoglobulin and aspirin under specialist care is best because timely IVIG with aspirin is standard treatment to reduce coronary complications in Kawasaki disease. B is less suitable because methotrexate does not treat Kawasaki disease; C is less suitable because allopurinol treats gout; D is less suitable because low-dose prednisolone alone is inadequate; E is less suitable because waiting risks coronary artery aneurysm. Clinical pearl: treatment is most effective when given early, but should still be considered after day 10 if inflammation persists.

Reference: British Paediatric Allergy Immunity and Infection Group guidance