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Primary hyperparathyroidism — SCE Rheumatology MCQ

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HardMetabolic Bone DiseasePrimary hyperparathyroidismSCE Rheumatology

A patient has confirmed primary hyperparathyroidism, adjusted calcium 2.70 mmol/L, a distal-radius T-score of −2.7 and recurrent renal stones. Kidney function is preserved. Which management recommendation is most appropriate?

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Correct answer: BRefer for assessment by a specialist parathyroid surgeon

Renal stones and osteoporosis are end-organ complications that meet NICE criteria for surgical referral in confirmed primary hyperparathyroidism. Cinacalcet can lower calcium and an antiresorptive can address skeletal risk in selected non-surgical patients, but neither replaces assessment for definitive parathyroid surgery here.

Reference: NICE NG132: primary hyperparathyroidism — recommendations (Published May 2019): https://www.nice.org.uk/guidance/ng132/chapter/Recommendations; NOGG clinical guideline for prevention and treatment of osteoporosis (Updated 2024): https://www.nogg.org.uk/full-guideline