Osteoporosis — SCE Rheumatology MCQ
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Correct answer: E — Vertebral compression fracture
Vertebral compression fracture is the single best answer because fragility fracture plus T-score below -2.5 indicates osteoporosis. The stem is testing complication screening, not isolated recall, so the relevant clinical pattern and risk context determine the answer. Osteomalacia is less suitable because it fits a different clinical pattern or a different treatment threshold; Multiple myeloma, Plain radiograph alone and Methotrexate do not address the key discriminator in this vignette. Clinical pearl: in SCE-style rheumatology questions, autoantibodies, imaging and synovial fluid findings should be interpreted with the whole phenotype.
Reference: NOGG osteoporosis guideline; NICE technology appraisals; BNF