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Nailfold capillaroscopy in Raynaud's — SCE Rheumatology MCQ

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ModerateMusculoskeletal InvestigationsNailfold capillaroscopy in Raynaud'sSCE Rheumatology

A 78-year-old man has Raynaud's phenomenon, puffy fingers, positive ANA and no established connective tissue disease. What is the most appropriate investigation?

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Correct answer: BNailfold capillaroscopy

Nailfold capillaroscopy is the single best answer because capillaroscopy can support secondary Raynaud's and systemic sclerosis-spectrum disease. The stem is testing investigation selection, not isolated recall, so the relevant clinical pattern and risk context determine the answer. Synovial fluid microscopy, Gram stain and culture is less suitable because it fits a different clinical pattern or a different treatment threshold; MRI of the sacroiliac joints, High-resolution CT chest and Renal biopsy do not address the key discriminator in this vignette. Clinical pearl: in SCE-style rheumatology questions, autoantibodies, imaging and synovial fluid findings should be interpreted with the whole phenotype.

Reference: BSR hot swollen joint guidance; EULAR imaging/autoantibody recommendations