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Takayasu arteritis in pregnancy — SCE Rheumatology MCQ

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HardPregnancy and Rare Rheumatic DiseaseTakayasu arteritis in pregnancySCE Rheumatology

A woman at 20 weeks’ gestation has active Takayasu arteritis with worsening arm claudication, new hypertension and progression of aortic-branch stenoses. What is the most appropriate management principle?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: E — Coordinate maternal, rheumatology and vascular teams and choose treatment according to gestational risk

Explanation lettering: E = shown as C · C = shown as D · D = shown as E

D is correct. Active large-vessel vasculitis in pregnancy requires multidisciplinary maternal and vascular care, pregnancy-compatible disease control and phenotype-specific treatment of hypertension or threatened organs. A permits maternal vascular injury and placental risk. B uses a contraindicated drug. C delays essential assessment. E ignores active inflammation, anatomy and maternal–fetal procedural risk.

Reference: BSR guideline on immunomodulatory anti-rheumatic drugs in pregnancy and breastfeeding: https://academic.oup.com/rheumatology/article/62/4/1370/6783014